Effect of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery
NCT07367542 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 218
Last updated 2026-01-27
Summary
A Dual-Center, Randomized, Controlled, Blinded, Prospective Study on the Effects of Esketamine on Perioperative Negative Emotions in Patients Undergoing Breast Cancer Surgery
Conditions
- Depression
- Anxiety
- S-ketamine
- Breast Cancer
Interventions
- DRUG
-
Esketamine 0.3mg/kg
A single dose of 0.3 mg/kg esketamine is administered intravenously during anesthesia induction, with the infusion completed over 40 minutes.
- DRUG
-
Normal Saline
Receiving the same volume of normal saline during induction of anesthesia during the same time
Sponsors & Collaborators
-
Beijing 302 Hospital
collaborator OTHER -
Chinese PLA General Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-17
- Primary Completion
- 2027-02-01
- Completion
- 2027-02-01
Countries
- China
Study Locations
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