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The Impact of Anxiety or Depression on the Sedative Concentration of Propofol

NCT03741361 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2019-07-09

No results posted yet for this study

Summary

120 consecutive female patients, 18-65 years old, American Society of Anesthesiologists (ASA) physical status I to II, scheduled for hysteroscopic surgery under propofol-based intravenous anesthesia will be recruited in this cohort study. The day before surgery, participants will be assessed the state of preoperative anxiety and depression. On the day of surgery, propofol will be administered by target controlled infusion (TCI) pump. During induction of anesthesia, the level of sedation will be evaluated. The induction dose of propofol, target effect-site concentration(Cet), plasma concentration(Cp) and effect-site concentration (Ce) of propofol will be recorded.

Conditions

Interventions

OTHER

anxiety and depression

Female patients who have a previous history of surgery or infertility, or a history of miscarriage or abortion are often susceptible to preoperative anxiety or depression. We will observe the effect of anxiety and depression on the dosage of propofol during induction.

Sponsors & Collaborators

  • Xuyu Zhang

    lead OTHER

Principal Investigators

  • Xuyu Zhang, M.D. and Ph.D · Department of Anesthesiology,The first affiliated hospital of Sun Yat-sen University

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-11-27
Primary Completion
2019-02-01
Completion
2019-02-15

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03741361 on ClinicalTrials.gov