Depression is a common mental disorder characterized by persistent low mood or loss of interest and pleasure over extended periods. It can impair social, occupational, and daily functioning, and in severe cases can lead to suicide. Effective treatments exist for mild, moderate, and severe depression.
A review of more than 200 studies linked up to a third of dementia cases to diseases outside the brain. Trials and broader evidence also support multi-domain prevention strategies.
A large analysis of 131,821 health professionals found that two to three cups of caffeinated coffee a day were linked to a 19 percent lower dementia risk. One daily cup of caffeinated tea was linked to a 14 percent lower risk.
AbbVie raised 2026 revenue and EPS guidance after first-quarter results beat estimates, with Skyrizi and Rinvoq driving growth. Humira erosion continued as neuroscience, oncology and pipeline assets supported the outlook.
A 12-week supervised remote exercise program for patients with metastatic renal cell carcinoma undergoing immunotherapy showed significant improvements in health-related quality of life, fatigue, and symptom burden in a case series of 19 patients.
Research and survey data point to lifelong learning, midlife stimulating activities and treatment of health risks as factors linked to better brain health and lower dementia risk.
A longitudinal study of 460,000 teenagers found adolescent cannabis use was linked to higher risks of later bipolar, psychotic, anxiety and depression diagnoses. Separate research and expert guidance say THC effects, especially long term, still need more study.
The FDA’s publication of complete response letters has tightened company disclosure around drug rejections and exposed common approval hurdles. Analyses of the letters point to frequent facilities and product quality deficiencies and delays averaging more than 2.5 years to final approval.
Diabetes and heart disease can impair sexual function by damaging blood vessels, nerves and circulation. Sexual dysfunction may also be an early warning sign of underlying vascular damage.
NRx said the FDA issued a positive review letter on its preservative-free ketamine ANDA, requesting only minor administrative changes. The company also received FDA guidance outlining a path to an NDA for NRX-100 using clinical trial data and real-world evidence.
A study in The Lancet Child & Adolescent Health linked academic pressure at age 15 to higher depressive symptoms through age 22 and self-harm risk through age 24.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07604389 |
AR Health Education Video for Postoperative Breast Cancer Patients |
RECRUITING | NA |
| NCT07599124 |
Effectiveness of Light Therapy Across Seasons |
COMPLETED | |
| NCT07592117 |
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Tavua, Fiji |
NOT_YET_RECRUITING | NA |
| NCT07591363 |
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RECRUITING | NA |
| NCT07582666 |
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COMPLETED | NA |
| NCT07582120 |
Psilocybin-Assisted Therapy as a Treatment for Depression |
NOT_YET_RECRUITING | PHASE2 |
| NCT07579481 |
Vortioxetine in Depression and Concomitant Migraine |
RECRUITING | |
| NCT07577947 |
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NOT_YET_RECRUITING | NA |
| NCT07577401 |
Calming Minds Study |
NOT_YET_RECRUITING | NA |
| NCT07574060 |
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NOT_YET_RECRUITING | PHASE2/PHASE3 |
