Depression is a common mental disorder characterized by persistent low mood or loss of interest and pleasure over extended periods. It can impair social, occupational, and daily functioning, and in severe cases can lead to suicide. Effective treatments exist for mild, moderate, and severe depression.
Michelle, a mental health therapist, was diagnosed with stage 4 lung cancer and given 24 months to live. Through yoga and meditation, she shifted her mindset and is now thriving six years after diagnosis, with tumors continuing to shrink.
UK data links 150+ deaths to weight-loss jabs. A new study finds a vegan diet led to 5.9kg average loss in 4 months vs 6.9kg over 9 months for semaglutide.
A Cochrane review found intermittent fasting did not beat standard diet advice for weight loss. A separate trial found it matched calorie restriction but felt less restrictive. Experts advise a case-by-case approach given limited evidence.
New research links gut microbiome composition to cancer immunotherapy outcomes. A 674-patient study showed gut bacteria predict melanoma recurrence with up to 94% accuracy, while other studies identified specific microbes influencing treatment response and resistance in melanoma and liver cancer.
FDA final guidance sets standards for psychedelic clinical trials. Federal agencies and states are advancing psilocybin and ibogaine research, and Eli Lilly is acquiring AtaiBeckley for $2.8 billion.
The global CNS therapeutics market was valued at USD 127.29 billion in 2025 and is projected to reach USD 285.72 billion by 2035, driven by demand for Alzheimer’s and Parkinson’s treatments. North America held 45% of the market; neurodegenerative diseases were the largest segment. Private investment and trends toward biologics and AI are shaping the sector.
Research shows depression can raise cancer mortality by 23–83%, and the emotional toll of a diagnosis may be compounded by seasonal mood changes. Experts urge integrating mental health support into cancer care to improve outcomes.
A digital mental health program significantly reduced anxiety in breast cancer survivors, with additional coaching helping depression, while a broader review finds eHealth tools improve psychological support in cancer care.
AbbVie posted record 2025 revenue of $61.2 billion and raised 2026 guidance on Skyrizi and Rinvoq growth. Pipeline advances include Crohn's submissions, obesity data, and European approval for Boey.
Kintsugi, a startup developing AI to detect depression and anxiety from voice, is shutting down and open-sourcing its technology due to costly FDA regulatory hurdles. The company’s models analyzed brief speech samples and showed significantly higher depression detection rates than standard questionnaires in a health payer trial. The release aims to empower global research into voice biomarkers for mental healthcare.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07773259 |
CODEPAD-III (Collaborative Outcomes of DEpression and Pain Associated With Delivery-III) |
NOT_YET_RECRUITING | NA |
| NCT07771413 |
Effect of a Telehealth Intervention on Depressive Symptoms Among Caregivers of Patients With Cerebral Palsy Receiving Home Care |
COMPLETED | NA |
| NCT07765355 |
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults |
RECRUITING | NA |
| NCT07760701 |
Description of the Lived Experiences of Family Caregivers for People With Mental Health Comorbidities |
COMPLETED | |
| NCT07755995 |
Latin Dance and Psychological Health in Primary School Children |
NOT_YET_RECRUITING | NA |
| NCT07744295 |
Preoperative Anxiety and Depression Among Older Chinese Patients |
NOT_YET_RECRUITING | |
| NCT07741422 |
Investigating a Mediation Model of Emotion Regulation and Psychological Resilience in Relationship Between Mindfulness and Negative Emotions Among College Students in Guangzhou |
COMPLETED | NA |
| NCT07737652 |
Microcurrent Neurofeedback as an Adjunct to Standard Care for Substance Use Disorders |
COMPLETED | NA |
| NCT07737366 |
The Efficacy of Lavender Herbal Tea in Premenstrual Syndrome |
COMPLETED | NA |
| NCT07736508 |
Systemic Couple Therapy for Marital Dynamics and Mental Health |
NOT_YET_RECRUITING | NA |
