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Monitoring the Clinical and Immunological Effects of Microbiome Changes Following Severe Burn Injury

NCT07329595 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-01-09

No results posted yet for this study

Summary

The aim of this study is to longitudinally monitor dynamic changes in the gut microbiome following severe burn injury using fecal samples. Under standard nutritional protocols and intensive care management, serial fecal sampling is performed to assess alterations in microbiome diversity and composition, as well as the indirect effects of these changes on measurable inflammatory biomarkers, endocrine, hematological, immunological, and other organ-specific parameters, the clinical course, and patient outcomes.

Conditions

  • Severely Burned Patients
  • Gut Microbiota Diversity and Composition
  • Inflammatory Responses

Sponsors & Collaborators

  • Tamas Vegh, MD

    lead OTHER

Principal Investigators

  • Lenke Jenei Kluch, MD · University of Debrecen

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-12-01
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Hungary

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07329595 on ClinicalTrials.gov