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IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients

NCT07345169 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 540

Last updated 2026-01-15

No results posted yet for this study

Summary

This is a prospective observational physiopathological study aimed at evaluating the immunological and inflammatory determinants associated with the prognosis of patients admitted to intensive care units (ICU). The study will establish multidimensional models predicting one-year survival and the occurrence of nosocomial infections.

Patients admitted to ICU undergo routine biological sampling. In addition to these, minimal supplementary samples will be collected for immunological and inflammatory biomarker analysis at admission, day 1, day 4, day 8, ICU discharge or day 28, and at 12 months. Additional samples may be taken during clinically significant events (nosocomial infections, complications).

Conditions

  • Critical Illness
  • Intensive Care Patients
  • Critical Illness Requiring Intensive Care - Sepsis
  • Critical Illness Requiring Intensive Care - Acute Brain Injury
  • Critical Illness Requiring Intensive Care - Major Surgery
  • Critical Illness Requiring Intensive Care - Polytrauma

Sponsors & Collaborators

  • INSERM U942

    collaborator UNKNOWN

  • Société Française d'Anesthésie et de Réanimation

    collaborator OTHER

  • French Society for Intensive Care

    collaborator OTHER

  • European Society of Intensive Care Medicine

    collaborator OTHER

  • ZOLL Foundation, Fondation Les Gueules Cassées

    collaborator UNKNOWN

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2031-02-28
Completion
2031-02-28

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07345169 on ClinicalTrials.gov