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Use of Subanesthetic Dose Propofol Before Extubation

NCT07276633 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2025-12-11

No results posted yet for this study

Summary

This study investigates whether administering a low, sub-anesthetic dose of propofol before extubation can reduce emergence agitation and improve perioperative comfort in patients undergoing rhinoplasty. Emergence agitation refers to restlessness and confusion during early recovery from anesthesia, which may affect patient safety and surgical conditions. The study evaluates agitation levels, recovery characteristics, and patient-reported comfort following propofol administration compared with standard care.

Conditions

  • Emergence Agitation
  • Rhinoplasty
  • Patient Satisfaction

Interventions

DRUG

Propofol (Sub-Anesthetic Dose)

Participants receive 0.5 mg/kg intravenous propofol as a single bolus 10 minutes before extubation.

OTHER

Normal Saline (Placebo)

Participants receive an equivalent volume of normal saline 10 minutes before extubation.

Sponsors & Collaborators

  • Yuzuncu Yil University

    lead OTHER

Principal Investigators

  • Nureddin Yuzkat, Associate professor · Yuzuncu Yil University Dursun Odabas Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-01
Primary Completion
2024-09-01
Completion
2024-10-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07276633 on ClinicalTrials.gov