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Blood Glucose Levels After Bread Consumption Between Participants With Normal Weight and Overweight/Obesity

NCT07158762 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2025-09-08

No results posted yet for this study

Summary

Obesity and increased blood glucose peaks are risk factors for type 2 diabetes mellitus (T2DM). Few studies have explored whether increased body fat contributes to higher blood glucose peaks after food consumption.

This study aimed to investigate differences in blood glucose levels between healthy adults with normal weight and those with overweight/obesity after consuming two commercially available breads (white and wholemeal) with different dietary fibre contents.

In this study, 20 healthy adults (10 normal weight, 10 overweight/obese) consumed two slices of white bread (100 g, fibre 3.6 g) or wholemeal bread (88 g, fibre 5.6 g) alongside 150 ml of orange juice and 10 g of butter on separate visits in random order after fasting for 8-12 hours. Blood glucose concentration was measured while fasting (before bread consumption) and at 30, 60, 90, and 120 minutes after consumption using finger-prick tests. Information on age, gender, ethnicity, body mass index (BMI), and body fat percentage (BF%) was also collected.

Conditions

  • Healthy Participants
  • Normal Weight Adults
  • Overweight or Obese Adults

Interventions

OTHER

White bread

Two slices of white bread consumption along with 150 ml of pure orange juice and 10 g of butter

OTHER

Wholemeal bread

Two slices of wholemeal bread consumption along with 150 ml of pure orange juice and 10 g of butter

Sponsors & Collaborators

  • Coventry University

    collaborator OTHER

  • City, University of London

    lead OTHER

Principal Investigators

  • Yizhi Xu, PhD · Coventry University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-05-01
Primary Completion
2022-07-31
Completion
2022-07-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07158762 on ClinicalTrials.gov