Predicting Outcomes in Posttransplant Diabetes Mellitus Via microRNA
NCT07055984 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 130
Last updated 2025-07-09
Summary
The study aims to improve the prediction and early detection of post-transplant diabetes mellitus (PTDM) in kidney transplant recipients. The investigators are investigating whether specific microRNA profiles measured 3 months after transplantation can reliably predict the development of PTDM within the following one to two years.
Additionally, the investigators are evaluating how traditional risk factors-such as age, immunosuppressive therapy, obesity, and infections like CMV-interact with these microRNA markers.
The ultimate goal of this research is to identify early indicators of blood sugar issues, enabling timely interventions to improve health outcomes and personalize patient care after kidney transplantation.
Conditions
- Diabetes Mellitus
- Kidney Transplant
Sponsors & Collaborators
-
University Hospital, Martin
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-04-28
- Primary Completion
- 2028-04-28
- Completion
- 2029-04-28
Countries
- Slovakia
Study Locations
More Related Trials
-
Deceased Donor Biomarkers and Recipient Outcomes
NCT01848249 ·Status: COMPLETED
-
Prospective Controlled Study of Posttransplant Diabetes
NCT00006331 ·Status: UNKNOWN
-
Hyperglycemia and (Pre)Diabetes in Pediatric Renal and Liver Transplantation.
NCT05464043 ·Status: COMPLETED ·Phase: NA
-
Renal Function Prediction in Living Donor Transplant Using Baseline Data
NCT06728995 ·Status: ACTIVE_NOT_RECRUITING
-
TransplantLines Insulin Resistance and Inflammation Biobank and Cohort Study
NCT03272854 ·Status: ACTIVE_NOT_RECRUITING
-
Multimorbidity and Cardiovascular Risk Factors After Renal Transplant
NCT07205692 ·Status: RECRUITING
-
The Study of Long-term Deterioration of Kidney Transplants.
NCT00217126 ·Status: COMPLETED
-
Predicting Mortality in Kidney Transplant Recipients
NCT06531967 ·Status: ENROLLING_BY_INVITATION
-
Long-term Cardiovascular Risk Following Successful Renal Transplantation
NCT01728012 ·Status: COMPLETED
-
MR-proADM as a Early Biomarker for DGF and AR in Kidney and Liver Transplantation
NCT06130046 ·Status: RECRUITING
-
Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients
NCT06025240 ·Status: RECRUITING
-
Exercise, Prediabetes and Diabetes After Renal Transplantation.
NCT04489043 ·Status: UNKNOWN ·Phase: NA
-
Association of Genetic Polymorphism and Acute Kidney Injury After Liver Transplantation
NCT02489474 ·Status: COMPLETED
-
Precision Risk Stratification in Kidney Transplant Patients - EU-TRAIN
NCT03652402 ·Status: COMPLETED
-
Impact of Glycemic Control After Reperfusion on Acute Kidney Injury in Living Donor Liver Transplantation
NCT06320730 ·Status: COMPLETED
-
Use of Predigraft in Kidney Transplant Patients
NCT04969757 ·Status: COMPLETED ·Phase: NA
-
Early Detection of de Novo Cancer in Liver Transplant Recipients
NCT05492617 ·Status: COMPLETED
-
MicroRNA Profile As a Biomarker of Liver Damage in Different Types of Liver Donors.
NCT06611046 ·Status: COMPLETED
-
A Clinical Trial to Prevent New Onset Diabetes After Transplantation
NCT01683331 ·Status: COMPLETED ·Phase: PHASE4
-
Prospective Evaluation of Predictors for Organ Failure Following Liver Transplantation
NCT00408889 ·Status: COMPLETED
-
GEnomic Medicine in Kidney Transplantation Study
NCT06365411 ·Status: NOT_YET_RECRUITING
-
DMEK Versus DSAEK Study
NCT02793310 ·Status: COMPLETED ·Phase: NA
-
Pro-active Genetic Testing in Kidney Transplant Patients
NCT05298904 ·Status: ACTIVE_NOT_RECRUITING
-
To Evaluate the Renal Tubular Function Pre and Post Nephrectomy in Living Donors
NCT03676361 ·Status: WITHDRAWN ·Phase: PHASE4
-
Limitation of Ischemic Injury of a Kidney Stored in Machine Perfusion in Hypothermia - Evaluation of the Impact on Kidney Allograft Function
NCT01731457 ·Status: COMPLETED ·Phase: PHASE2