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GEnomic Medicine in Kidney Transplantation Study

NCT06365411 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2025-03-28

No results posted yet for this study

Summary

Investigator led, prospective, observational cohort study to detect genomic features which can predict outcomes following kidney transplantation.

1. Determine non-HLA genomic mismatches between donor-recipient pairs which impact kidney allograft survival following transplantation
2. Derive polygenic risk scores on pre-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction
3. Derive polygenic risk scores on post-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction

Conditions

  • Transplant Complication
  • Kidney Transplant Rejection

Interventions

DIAGNOSTIC_TEST

Biomarker discovery and validation - with focus on genomic biomarkers

Biomarker discovery and validation - with focus on genomic biomarkers

Sponsors & Collaborators

  • Western Sydney Local Health District

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-03
Primary Completion
2030-01-01
Completion
2035-01-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06365411 on ClinicalTrials.gov