MR-proADM as a Early Biomarker for DGF and AR in Kidney and Liver Transplantation
NCT06130046 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-08-01
Summary
To define the sensibility and the specificity of increased levels of MR-proADM for early, non-invasive, diagnosis of AR and DGF after kidney and liver transplantation creating a predictive model for related complications after kidney and liver transplantation based on the pre-operative and post-operative levels of MR-proADM and by a machine learning process.
Conditions
- Kidney Transplant; Complications
- Liver Transplant; Complications
Interventions
- BIOLOGICAL
-
MR-proADM dosage
Dosage of MR proADM at OLT/KT, 1, 3, 5, 15 POD and 1, 3, 6, 9, 12 months F-U
Sponsors & Collaborators
-
University of Rome Tor Vergata
lead OTHER
Principal Investigators
-
Roberta Angelico, PhD FEBS · University of Rome Tor Vergata
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-12-01
- Primary Completion
- 2026-05-01
- Completion
- 2026-12-01
Countries
- Italy
Study Locations
More Related Trials
-
Development and Validation of a Multidimensional Score to Predict Long-term Kidney Transplant Outcomes
NCT03474003 ·Status: COMPLETED
-
Urinary Transglutaminase 2 as a Biomarker for Kidney Allograft Fibrosis
NCT03487861 ·Status: UNKNOWN
-
Biomarkers of Kidney Function in Transplant Medicine
NCT05538234 ·Status: RECRUITING
-
Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors
NCT06171438 ·Status: COMPLETED
-
Renal Biopsies in Post-liver Transplantation Patients With Renal Impairment
NCT05326399 ·Status: RECRUITING
-
Transcriptomics as an Aid in the Histological Diagnosis of Acute Rejection After Liver Transplantation
NCT06734013 ·Status: RECRUITING ·Phase: NA
-
Correlation of Molecular Biomarkers With Biopsy Findings and Outcomes in Renal Transplant Recipients
NCT02463253 ·Status: COMPLETED
-
Identification of Markers (Klotho-FGF23 Axis) as Determinant in the Evolution of Arterial Stiffness During the First Year of Renal Transplant
NCT02951442 ·Status: COMPLETED ·Phase: NA
-
Biomarkers and Inflammation in Solid Organ Transplantation: Relationship With Short- and Long-Term Outcomes
NCT06774339 ·Status: RECRUITING
-
BIOMARGIN European, Ambispective Cohort of Adult and Paediatric Renal Transplant Patients
NCT02832661 ·Status: UNKNOWN
-
Technology Enabled And Molecular Monitoring of the Allograft and Transplant rEcipient
NCT05033548 ·Status: TERMINATED
-
Search for Noninvasive Markers of "Graft Injury" in Pediatric and Adult Patients With Congenital Heart Disease Undergoing Cardiac Transplantation
NCT06784440 ·Status: RECRUITING ·Phase: NA
-
Longitudinal Follow-up and Health-Related Outcomes in Liver Transplant Recipients and Living Donors
NCT07301853 ·Status: RECRUITING
-
Development and Validation of a Clinical Risk Prediction Model for Early Acute Kidney Injury Within 48 Hours After Liver Transplantation
NCT06750770 ·Status: COMPLETED
-
New Urine and Blood Markers for Acute Kidney Injury in Liver Transplant Patients
NCT00855127 ·Status: WITHDRAWN
-
Renal and Cardiac Risk Factors of AKI After Liver Transplantation
NCT05666232 ·Status: UNKNOWN
-
A Study of Novel Biomarkers of Kidney Dysfunction at Liver Transplant
NCT03376009 ·Status: COMPLETED
-
Prediction of Chronic Allograft Nephropathy
NCT01380847 ·Status: COMPLETED
-
Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients
NCT05793203 ·Status: RECRUITING
-
Renal Transporters After Renal Transplantation
NCT00427024 ·Status: UNKNOWN
-
Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.
NCT06717542 ·Status: RECRUITING ·Phase: NA
-
Metabolite Biomarkers Related to Acute Rejection in Kidney Transplantation
NCT03134625 ·Status: UNKNOWN
-
Deep Phenotyping of the Renal Allograft to Prognosticate Clinical Outcomes
NCT06438107 ·Status: NOT_YET_RECRUITING
-
Predicting Outcomes in Posttransplant Diabetes Mellitus Via microRNA
NCT07055984 ·Status: RECRUITING
-
Pre-formed Alloreactivity in Renal Transplant Recipients
NCT02633826 ·Status: COMPLETED