Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults
NCT06942351 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2025-06-19
Summary
The purpose of this study is to examine the impact of daily consumption of walnuts for 12 weeks on cognitive function, markers of inflammation and oxidative stress, and the gut microbiome in healthy adults age 55 years and older.
Conditions
- Aging
- Inflammation Biomarkers
Interventions
- OTHER
-
Walnuts
Daily consumption of 1.5 ounces of plain walnuts for 12 weeks
- OTHER
-
Crackers
Daily consumption of non-whole grain crackers for 12 weeks (caloric equivalent to 1.5 ounces of plain walnuts)
Sponsors & Collaborators
-
California Walnut Commission
collaborator OTHER -
Oregon State University
lead OTHER
Principal Investigators
-
Emily Ho, PhD · Oregon State University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-06-09
- Primary Completion
- 2028-12-31
- Completion
- 2029-05-31
Countries
- United States
Study Locations
More Related Trials
-
Effects of California Walnuts on Vascular Function in Postmenopausal Women
NCT01072864 ·Status: COMPLETED ·Phase: PHASE1
-
The Effect of Pistachio-Rich Breakfast Meals on Cognitive Function in Healthy Older Adults
NCT06900452 ·Status: RECRUITING ·Phase: NA
-
The Metabolic Effect of Walnut Consumption in Healthy Men and Healthy Postmenopausal Women
NCT01188902 ·Status: COMPLETED ·Phase: NA
-
Snacks and Brain Health
NCT07348406 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1/PHASE2
-
The Impact of Cranberries On the Microbiome and the Brain in Healthy Ageing sTudy (COMBAT)
NCT03679533 ·Status: COMPLETED ·Phase: NA
-
Influence of Walnut Intake on Vascular Function and Metabolism
NCT03900403 ·Status: COMPLETED ·Phase: NA
-
Walnuts and Healthy Aging
NCT01634841 ·Status: COMPLETED ·Phase: NA
-
Effects of Time of Day and Nut Intake on Cognitive Performance
NCT06343142 ·Status: COMPLETED ·Phase: NA
-
The Effect of Consumption of Almonds and Snack Mix Daily for 6 Months on Cognitive Function in Older Adults
NCT03093896 ·Status: COMPLETED ·Phase: NA
-
Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
NCT06735599 ·Status: RECRUITING ·Phase: NA
-
Dietary Wild Blueberries and Joint Health
NCT06828159 ·Status: RECRUITING ·Phase: NA
-
Interindividual Variation in Response to Green Coffee
NCT06204445 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
NCT06735651 ·Status: RECRUITING ·Phase: NA
-
Effect of Daily Mixed Spice Consumption on Memory Function
NCT06889961 ·Status: RECRUITING ·Phase: NA
-
AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults
NCT06137339 ·Status: RECRUITING ·Phase: NA
-
Cognition, Flavonoids, Exercise, Gut Microbiome
NCT06495190 ·Status: RECRUITING ·Phase: NA
-
Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk
NCT04431960 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Wheat Bran Extract on Cognitive and Memory Function
NCT02489747 ·Status: COMPLETED ·Phase: NA
-
Acute and Chronic Effects of Avena Sativa on Cognition and Stress
NCT03689348 ·Status: COMPLETED ·Phase: NA
-
Mechanistic Effect of Walnut Consumption on Sleep Quality
NCT06430086 ·Status: RECRUITING ·Phase: NA
-
Whole Coffee Cherry Study
NCT04986956 ·Status: COMPLETED ·Phase: NA
-
Anthocyanin & Phenolic Acids Bioavailability & Antioxidant Capacity After Consumption of Purple Wheat Products in Adults
NCT02730910 ·Status: COMPLETED ·Phase: NA
-
Investigating the Acute Effects of Flavonoids in Blueberries on Cognitive Function.
NCT01289860 ·Status: COMPLETED ·Phase: NA
-
Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers
NCT06780774 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Strawberries, Cognition, and Vascular Health
NCT04786665 ·Status: COMPLETED ·Phase: NA