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Estrogen and Propofol Injection Pain

NCT06929416 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2025-09-16

No results posted yet for this study

Summary

This prospective observational study investigates the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing general anesthesia. The study will include 90 ASA I-II female patients aged 18-45. One group will consist of IVF patients with elevated estrogen levels, while the control group will include patients with normal estrogen levels undergoing other elective procedures. Pain will be assessed using a standardized four-point behavioral pain scale. The findings may enhance understanding of hormonal influences on pain and contribute to improving patient comfort during anesthesia induction.

Conditions

  • Pain
  • Estradiol
  • Assisted Reproductive Techniques

Sponsors & Collaborators

  • Konya City Hospital

    lead OTHER

Principal Investigators

  • Mahmut Tutar, MD · KONYA CITY HOSPİTAL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-02
Primary Completion
2025-09-10
Completion
2025-09-10

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06929416 on ClinicalTrials.gov