Detection of Sepsis Occurrence by Using Blood Fluorescence

NCT06745115 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2024-12-20

No results posted yet for this study

Summary

This study adopted a case-control study method to explore a reagent-free, highly sensitive, and frequently screened blood fluorescence metabolite analyzer for sepsis, which can detect the emergence of inflammatory free radicals before organ damage and shorten the diagnosis time of sepsis.

Conditions

Sepsis

Interventions

DIAGNOSTIC_TEST

Blood fluorescence metabolite analyzer

This study does not involve Intervention. The fluorescence intensity quantified by the blood fluorescence metabolite analyzer does not affect or interfere with clinical diagnosis and treatment. In both the early and late stages of sepsis, a significant increase in inflammatory free radicals changes the optical properties of the patient's blood, distinguishing it from that of healthy individuals. To explore this phenomenon, 10 cc of fasting blood is drawn from patients who pass our screening criteria. This sample is then centrifuged in accordance with our detailed standard operating procedures to ready it for analysis. Subsequently, the fluorescence intensity of the blood is measured quantitatively using a precisely calibrated blood fluorometer, which is specifically designed to detect subtle variations indicative of both early and late sepsis. This entire process is executed under stringent quality control protocols to ensure the reliability and accuracy of the results.

Sponsors & Collaborators

University of Macau
collaborator OTHER
Zhujiang Hospital
lead OTHER

Eligibility

Min Age: 18 Years
Sex: ALL
Healthy Volunteers: Yes

Timeline & Regulatory

Start: 2023-09-09
Primary Completion: 2025-06-30
Completion: 2027-10-01

Countries

China

Study Locations

More Related Trials

Entities

Diseases

Sepsis