Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Without early recognition and treatment, it can progress to septic shock, multi-organ failure, and death.
New research: any cardiometabolic risk factor justifies MASLD screening in overweight adults, and MASLD independently worsens sepsis, bleeding, and other outcomes in hospitalized Crohn's disease patients.
Studies reveal how kinin receptor antagonists achieve subtype selectivity and identify BDNF as a direct TLR4 antagonist, highlighting BDP-12 as a potential therapy for acute inflammatory diseases.
ImmunityBio establishes wholly owned subsidiary in Saudi Arabia to distribute Anktiva for bladder and lung cancer across MENA region, following world's first lung cancer approval in the Kingdom less than a year after May 2025 meeting.
Scientists at Northwell Health's Feinstein Institutes have developed a novel drug discovery strategy transforming a detrimental immune element into a therapeutic for sepsis and rheumatoid arthritis, published in Military Medical Research.
Sixty Republican members of Congress filed an amicus brief supporting Louisiana's lawsuit to restore in-person dispensing requirements for mifepristone, challenging Biden-era rules allowing mail-order abortion drugs.
Researchers have developed attenuated Listeria bacteria therapies that boost innate immune cells to fight cancer. Two approaches target colorectal cancer and pediatric leukemia, with FDA clearance expected soon for trials in children.
The FDA approved pembrolizumab (Keytruda) and Keytruda Qlex plus paclitaxel, with or without bevacizumab, for adults with PD-L1+ platinum-resistant ovarian carcinoma based on Phase 3 trial data showing improved survival outcomes.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07779720 |
Personalized Fluid Resuscitation in the Emergency Department: A Pilot Trial |
RECRUITING | NA |
| NCT07778004 |
ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers |
NOT_YET_RECRUITING | NA |
| NCT07774962 |
Discordance Between Capillary Refill Time and Oxygen Extraction Ratio in Septic Shock |
RECRUITING | |
| NCT07774013 |
Point of Care - Sepsis Study |
NOT_YET_RECRUITING | |
| NCT07770347 |
Immunity in Critical Sepsis |
ENROLLING_BY_INVITATION | NA |
| NCT07760415 |
EEG Changes and Cognitive Profiles in Sepsis Patients With Different Inflammatory Phenotypes |
NOT_YET_RECRUITING | |
| NCT07755033 |
Personalized Nutritional Formula for ICU Patients: A Study on Prognosis and Multidimensional Health Markers |
NOT_YET_RECRUITING | NA |
| NCT07746050 |
Value of Biomarkers of Brain Injury for Predicting Psycho-cognitive Sequelae Secondary to Sepsis: a Prospective Multicenter Study |
NOT_YET_RECRUITING | NA |
| NCT07740304 |
Peripheral Perfusion Index Trajectory to Predict 28-Day Mortality in Patients With Sepsis in the Intensive Care Unit |
RECRUITING | |
| NCT07739251 |
Relation of Serum Phosphate Level to the Duration of Mechanical Ventilation in Patient With Sepsis |
NOT_YET_RECRUITING |
