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mNGS vs Culture Critically Ill Patients

NCT03760315 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 210

Last updated 2022-08-05

No results posted yet for this study

Summary

mNGS is popular in research and recently it has been used clinically to detect microbes in the blood or other secretion in infected patients for quicker ,broad and accurate detection of microbes. In ICU ,patients are critically ill and need quicker and accurate antibiotics use to stop the pathologic process. The purpose of this study was to determine whether the positive detection rate of pathogens in patients with sepsis by metagenomic full-targeted detection technology was higher than that in blood culture, and to determine whether the pathogens found in patients with sepsis by metagenomic full-targeted detection technology were important for clinical development. Anti-infective regimens can help.

Conditions

Interventions

DIAGNOSTIC_TEST

blood mNGS (IDSeqTM Ultra); blood Culture

take blood samples for mNGS and Culture at the same time in sepsis patients. No intervention on the treatment of the patients.

Sponsors & Collaborators

  • The First Affiliated Hospital with Nanjing Medical University

    collaborator OTHER

  • Northern Jiangsu People's Hospital

    collaborator OTHER

  • Southeast University, China

    lead OTHER

Principal Investigators

  • Haibo Qiu, MD · Southeast University, China

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2022-12-30
Completion
2022-12-30

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03760315 on ClinicalTrials.gov