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Effects on Septic Patient's Microcirculation of the Transfusion of Different Types of Concentrated RBCs.

NCT01584999 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2012-05-23

No results posted yet for this study

Summary

Aim of the study is to evaluate the effects, on microcirculation of septic patient, of three types of RBCs: 1- fresh standard RBCs (storage \<10 days); 2-leukodepleted RBCs and 3-old standard RBCs (storage \>15 days) respectively. Before and 1 hour after the transfusion, microcirculation is evaluated using Sidestream Dark Field Imaging (SDF) and Near InfraRed Spectroscopy (NIRS) with vascular occlusion test. We also monitor temperature, heart rate, mean blood pressure, hemochrome, blood gases, blood lactates and SOFA score.

Conditions

  • Septic Patients

Interventions

BIOLOGICAL

Blood transfusion

RBCs have been transfused in septic patient admitted in ICU

Sponsors & Collaborators

  • Azienda Ospedaliero, Universitaria Ospedali Riuniti

    collaborator OTHER

  • Università Politecnica delle Marche

    lead OTHER

Principal Investigators

  • Abele Donati, MD · Università Politecnica delle Marche

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2012-02-29

Countries

  • Italy

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01584999 on ClinicalTrials.gov