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Characterisation of Endothelial Cells in Different Inflammatory Pathologies

NCT06613256 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2024-09-25

No results posted yet for this study

Summary

The goal of this observational study is to characterise changes in gene expression in endothelial cells in patients with either sepsis or post major abdominal surgery.

The main question we plan to answer is: 'What molecular pathways are differentially expressed during inflammatory pathologies?'

Conditions

Interventions

OTHER

Endothelial cell biopsy

Endothelial cell sample collected from the antecubital fossa of patients. A vein in the antecubital fossa is cannulated with a 20 g valveless cannula. A metal guidewire is then passed into the vessel to collect endothelial cells for analysis

Sponsors & Collaborators

  • University of Surrey

    collaborator OTHER

  • Royal Surrey County Hospital NHS Foundation Trust

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-16
Primary Completion
2026-07-17
Completion
2026-11-12

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06613256 on ClinicalTrials.gov