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Identification of Markers of Poor Clinical Prognosis in Sepsis by Epigenetic Analysis

NCT06446947 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2026-02-12

No results posted yet for this study

Summary

Sepsis is a multifactorial syndrome characterized by a dynamic course and a clinical outcome dependent on several factors, and responsible for one in five deaths worldwide. The aim of this trial is to identify new prognostic markers for the progression of sepsis to septic shock, by comparing epigenetic markers between patients who have or have not developed severe forms of sepsis.

The main objective of this preliminary study is to identify prognostic markers for the progression of sepsis to septic shock, i.e. to compare targeted markers between subjects with sepsis who progress to septic shock versus subjects with sepsis who do not progress to septic shock.

Conditions

  • Sepsis Syndrome
  • Septic Shock
  • Sepsis

Interventions

OTHER

blood sampling

Blood sampling (6ml) on admission and a second on discharge from intensive care.

Sponsors & Collaborators

  • Assistance Publique Hopitaux De Marseille

    lead OTHER

Principal Investigators

  • François CREMIEUX · Assistance Publique Hopitaux De Marseille

Eligibility

Min Age
45 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-20
Primary Completion
2026-09-30
Completion
2026-09-30

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06446947 on ClinicalTrials.gov