Establishing Reference Ranges for Fat-Soluble Vitamins in Healthy Chinese Adults

Summary

Vitamins are essential micronutrients required for maintaining normal physiological functions and metabolism in humans. Among them, fat-soluble vitamins (FSV) such as vitamins A, D, E, and K are absorbed in the intestines in the presence of fat. Both deficiencies and excesses of these vitamins can affect health. Current global studies on FSVs in healthy populations are often limited to specific types or regions, and comprehensive data on all four FSVs in the healthy Chinese population are lacking. This study aims to fill this gap by collecting and analyzing FSV levels from healthy adults across multiple regions in China, establishing a reference range for clinical evaluation and early disease intervention.

Conditions

• Fat Soluble Vitamin Deficiencies and Disorders

Interventions

OTHER

This is a cross-sectional study without intervention.

Sponsors & Collaborators

• Huizhou Municipal Central Hospital

  collaborator OTHER

• Affiliated Hospital of Jiaxing University

  collaborator OTHER

• Zhejiang Provincial Tongde Hospital

  collaborator OTHER

• Affiliated Yueqing Hospital of Wenzhou Medical University

  collaborator OTHER

• Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University

  collaborator OTHER

• Zhejiang Provincial People's Hospital

  collaborator OTHER

• Affiliated Hangzhou First People's Hospital

  collaborator UNKNOWN

• Ningbo Medical Center Lihuili Hospital

  collaborator OTHER_GOV

• Lu'an People's Hospital of Anhui Province

  collaborator UNKNOWN

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• Second Affiliated Hospital of Nanchang University

  collaborator OTHER

• The First Affiliated Hospital of Nanchang University

  collaborator OTHER

• Nanfang Hospital, Southern Medical University

  collaborator OTHER

• The Third Xiangya Hospital of Central South University

  collaborator OTHER

• Changzhi Medical College

  collaborator OTHER

• LinFen People's Hospital

  collaborator UNKNOWN

• The Second Affiliated Hospital of Chongqing Medical University

  collaborator OTHER

• Yulin No.2 Hospital

  collaborator OTHER

• Hanzhong Central Hospital

  collaborator OTHER

• First Affiliated Hospital of Zhejiang University

  lead OTHER

Principal Investigators

• Zhong Liu · First Affiliated Hospital of Zhejiang University

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-07-03

Primary Completion

2026-06-30

Completion

2026-08-02

Countries

• China

Study Locations