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Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol

NCT00678834 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2014-09-16

Study results available
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Summary

Levels of tocotrienol in human tissues following supplementation is not currently known. The objective of this present study is to determine the levels of this form of vitamin E in the human tissues such as skin, heart, lung, liver, adipose tissue, Brain and cerebrospinal fluid (CSF) following oral supplementation

Conditions

  • End Stage Cardiac Failure
  • Pulmonary Failure
  • End Stage Liver Disease
  • Morbid Obesity
  • Recalcitrant Epilepsy Requiring Surgery
  • Healthy Subjects

Interventions

DIETARY_SUPPLEMENT

To surgery patients, Tocopherol capsules.

200mg (2 100mg capsules) to take by mouth twice daily to total 400mg daily

DIETARY_SUPPLEMENT

Tocotrienol to healthy subjects.

200 mg to take orally two times a day (400 mg a day).

DIETARY_SUPPLEMENT

To surgery patients, Tocotrienol capsules.

200mg (2 100mg capsules) to take by mouth twice daily to total 400mg daily

Sponsors & Collaborators

  • Carotech Inc.

    collaborator INDUSTRY

  • Chandan K Sen

    lead OTHER

Principal Investigators

  • Chandan Sen, PhD · Ohio State University

Study Design

Allocation
RANDOMIZED
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-03-31
Primary Completion
2012-06-30
Completion
2012-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00678834 on ClinicalTrials.gov