MedTrace Logo

Effect of Fluid Regimen on Acute Kidney Injury

NCT06256120 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2024-11-26

No results posted yet for this study

Summary

Postoperative acute kidney injury (AKI) is an important surgical complication that increases hospital stay and mortality when it occurs after kidney surgery. Studies investigating the effects of restrictive or liberal fluid regimen on postoperative AKI during radical/partial nephrectomy have given controversial results. It is important to recognize AKI early so that supportive treatments can be started early. Serum creatinine level, which is frequently used in the detection of AKI, increases late and causes a delay in diagnosis. It has been reported that cystatin C level increases earlier than creatinine in the diagnosis of AKI, so it can be used for early diagnosis.

Conditions

Interventions

DIAGNOSTIC_TEST

Restrictive

3 mL/kg/hour Ringer Lactate will be given peroperatively to the restrictive group (Group R).

DIAGNOSTIC_TEST

Liberal

7 ml/kg/hour Ringer Lactate will be given peroperatively to the liberal group (Group L).

Sponsors & Collaborators

  • Muğla Sıtkı Koçman University

    lead OTHER

Principal Investigators

  • Eylem Yasar, M.D · Mugla Sitki Kocman Training and Research Hospital

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-29
Primary Completion
2024-06-15
Completion
2024-06-20

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06256120 on ClinicalTrials.gov