Network Analysis of Urinary Molecular Signature Complements Clinical Data to Predict Postoperative Acute Kidney Injury
NCT02114138 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 240
Last updated 2025-07-18
Summary
The risk for postoperative acute kidney injury (pAKI), as for any other postoperative complications (PC), comes from a number of interactions between a patient's health before surgery, strength to tolerate surgery and influences on the operating room environment. At this time doctors do not have good tools to predict which patients may be at risk of having this complication. The purpose of this research study is to develop a urine test that can be used to predict the risk for having problems with kidney function after major surgery.
Conditions
Interventions
- PROCEDURE
-
pathogenesis of perioperative acute kidney injury
understand pathogenesis of perioperative acute kidney injury in elective and emergent surgery
- DIAGNOSTIC_TEST
-
urine collection
urine collection will be performed on both the control group and hospitalized participants
Sponsors & Collaborators
-
University of Florida
lead OTHER
Principal Investigators
-
Azra Bihorac, MD · University of Florida
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-07-31
- Primary Completion
- 2030-06-30
- Completion
- 2030-12-31
Countries
- United States
Study Locations
More Related Trials
-
Evaluating Novel Biomarkers in Acute Kidney Injury
NCT01573104 ·Status: COMPLETED ·Phase: NA
-
Diagnostic Performance of Two Tools
NCT05268211 ·Status: UNKNOWN
-
Machine Learning Models for Prediction of Acute Kidney Injury After Noncardiac Surgery
NCT06146829 ·Status: COMPLETED
-
Nephroprotective Measures in Critically Ill Patients With Moderate/Severe Acute Kidney Injury
NCT06472999 ·Status: RECRUITING
-
Acute Kidney Injury - Biomarkers in Major Abdominal Surgery
NCT04582747 ·Status: COMPLETED
-
To Examine Whether Urinary Partial Oxygen Pressure Measurements Are Indicative of the Postoperative Occurrence of Acute Kidney Injury (AKI) in Individuals Who Have Undergone Liver Transplantation
NCT06121167 ·Status: NOT_YET_RECRUITING
-
Renal Oxygen Saturation and Its Association With Acute Renal Injury
NCT03608956 ·Status: WITHDRAWN
-
Effect of an Intervention to Prevent Acute Kidney Injury Versus Standard Care in High-risk Patients After Major Surgery
NCT05275218 ·Status: RECRUITING ·Phase: NA
-
Predictive Nomogram for Postoperative Acute Kidney Injury in Older Patients Undergoing Noncardiac Surgery
NCT05507268 ·Status: UNKNOWN
-
Preventing Acute Kidney Injury and Improving Outcome in Critically Ill Patients Utilising Risk Prediction Score
NCT03178435 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Postoperative Acute Kidney Injury (AKI) Incidence and Risk Factors in Patients Underwent Pneumonectomy
NCT05672238 ·Status: COMPLETED
-
Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative Patients
NCT02499185 ·Status: TERMINATED ·Phase: PHASE4
-
Serum Phosphatemia Predictive Marker for AKI Diagnosis After Cardiac Surgery
NCT02900313 ·Status: COMPLETED ·Phase: NA
-
Strategy for Uptake of Processes for Recognizing and Responding to Acute Kidney Injury
NCT03564314 ·Status: COMPLETED ·Phase: NA
-
Acute Kidney Injury as a Risk Factor for Myocardial Injury and Ventricular Dysfunction
NCT04768751 ·Status: COMPLETED
-
Assessment of AI Prediction Models in Prediction of Acute Kidney Injury in Critical Patients
NCT06857188 ·Status: NOT_YET_RECRUITING
-
Novel Biomarkers and Postoperative Kidney Injury in Radical Nephrectomy
NCT07088874 ·Status: RECRUITING
-
Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury
NCT01531985 ·Status: COMPLETED
-
Early Prediction of Acute Kidney Injury Among Patients Admitted to Surgical ICU
NCT04554628 ·Status: COMPLETED ·Phase: NA
-
Machine Learning Predict Acute Kidney Injury in Patients Following Cardiac Surgery
NCT04966598 ·Status: COMPLETED
-
Hematologic Ratios in Postoperative Acute Kidney Injury
NCT03658148 ·Status: WITHDRAWN
-
Predicting Adverse Kidney Events of Cardiac Surgery-Associated Acute Kidney Injury Using Novel Biomarkers
NCT06351813 ·Status: NOT_YET_RECRUITING
-
Development and Validation of a Real-time Prediction Model for Acute Kidney Injury in Hospitalized Patients
NCT06597838 ·Status: RECRUITING
-
AKI in Thoracic and Abdominal Surgery
NCT02553174 ·Status: TERMINATED
-
Identification of Patients at Risk of CKD After AKI
NCT05740709 ·Status: RECRUITING