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Effects of Oral Protein Load on Kidney Function in Patients Undergoing Cardiac Surgery

NCT03102541 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 214

Last updated 2018-11-20

No results posted yet for this study

Summary

Acute kidney injury (AKI) occurs in approximately one-third of patients undergoing cardiac surgery (CS), and represents one of the most significant negative predictors of patient outcome in this population. In the healthy adult, a high protein meal is known to enhance glomerular filtration rate and is mediated by an increase in renal blood flow. The investigators hypothesized that preoperative oral protein load may precondition the kidneys for upcoming insults and reduce the rate of postoperative AKI and long-term renal outcome.

Conditions

Interventions

OTHER

None intervention

Sponsors & Collaborators

  • University of Giessen

    lead OTHER

Principal Investigators

  • Claudio Ronco, MD · International Renal Research Institute of Vicenza, Vicenza, Italy

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-11-01
Primary Completion
2015-10-31
Completion
2016-11-24

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03102541 on ClinicalTrials.gov