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Prediction of Acute Kidney Injury After Cardiac Surgery With Cardiopulmonary Bypass

NCT07343830 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 455

Last updated 2026-02-04

No results posted yet for this study

Summary

Acute kidney injury (AKI) is a common and serious complication following cardiac surgery performed under cardiopulmonary bypass and is associated with increased morbidity, mortality, and prolonged hospital stay. Despite advances in perioperative management, the ability to accurately predict postoperative AKI remains limited.

Recent evidence suggests that preoperative inflammatory markers derived from routine laboratory tests, as well as indicators of intraoperative perfusion stress, may play an important role in the development of AKI. However, data evaluating these factors together in patients undergoing cardiac surgery with cardiopulmonary bypass are limited.

This retrospective observational cohort study aims to investigate the association between preoperative renal function, inflammatory indices, and intraoperative perfusion-related parameters with the development of postoperative AKI. Acute kidney injury will be defined according to the KDIGO serum creatinine criteria within the first 72 hours after surgery. The findings of this study may help identify patients at increased risk for AKI and contribute to improved perioperative risk stratification in cardiac surgery.

Conditions

  • Acute Kidney Injury
  • Cardiac Surgery
  • Cardiopulmonary Bypass Surgery
  • Cardiac Surgery Associated - Acute Kidney Injury

Sponsors & Collaborators

  • Ataturk University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-30
Primary Completion
2026-02-02
Completion
2026-02-02

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07343830 on ClinicalTrials.gov