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Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD

NCT06186869 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-03-27

No results posted yet for this study

Summary

The aim of the study is to estimate the effectiveness of two different exercise programs combined with the Mediterranean diet versus diet alone on inflammatory status in subjects aged 18-65 years with obesity (BMI\>30) and Non-Alcoholic Fatty Liver Disease (NAFLD) (CAP \>248 dB/m).

Conditions

Interventions

BEHAVIORAL

Aerobic Exercise and diet intervention

subjects randomized and assigned to one intervention group, will follow the low glycaemic index Mediterranean diet and simultaneously perform moderate-intensity aerobic exercises

BEHAVIORAL

Hiit and diet intervention

subjects randomised and assigned to one intervention group, will follow the low glycaemic index Mediterranean diet and simultaneously perform high-intensity interval exercises in the gym

BEHAVIORAL

Diet

subjects randomised and assigned to this intervention group will follow the low-glycaemic index Mediterranean diet

Sponsors & Collaborators

  • Antonella Bianco

    collaborator UNKNOWN

  • Isabella Franco

    collaborator UNKNOWN

  • Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

    lead OTHER

Principal Investigators

  • Endrit Shahini, MD · IRCCS Saverio de Bellis

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-02
Primary Completion
2025-12-15
Completion
2026-12-23

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06186869 on ClinicalTrials.gov