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Molecular Mechanisms Underpinning Sarcopenic Obesity

NCT06120647 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2023-12-11

No results posted yet for this study

Summary

The coexistence of obesity and sarcopenia results in sarcopenic obesity, a high-risk geriatric condition associated with metabolic perturbations and several co-morbidities. Despite the rising numbers of older adults diagnosed with sarcopenic obesity, few studies have characterized this condition on the muscle cell and systemic level. This study sought to comprehensively assess the influence of sarcopenic obesity on muscle and blood-related parameters and compare it to non-sarocopenic obese and non-sarcopenic lean older adults.

Conditions

Interventions

DIETARY_SUPPLEMENT

Essential amino acids (EAA)

intake of 240 mg EAA per kg lean body mass after a resistance exercise session

Sponsors & Collaborators

  • The Swedish School of Sport and Health Sciences

    lead OTHER

Principal Investigators

  • William Apró, PhD · The Swedish School of Sport and Health Sciences and Karolinska Institute, Stockholm Sweden

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-28
Primary Completion
2025-12-15
Completion
2025-12-30

Countries

  • Sweden

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06120647 on ClinicalTrials.gov