Sarcopenia is an age-related loss of muscle mass and strength that can impair daily function and increase risks such as falls and injuries. It is recognized as a diagnosable disease entity in ICD-10-CM.
GLP-1 drugs are still being studied for Alzheimer’s and addiction after semaglutide failed to slow cognitive decline in Alzheimer’s. A 2025 abstract reported semaglutide slowed cognitive impairment in an Alzheimer’s model.
Market analysis reports project substantial growth through 2033 across sarcopenia treatments, oncology injection drugs, and ASO-based therapies. Major pharmaceutical companies including Pfizer, Merck, Roche, Novartis, and Amgen feature prominently across all three therapeutic areas. The reports cover market segmentation, geographic analysis, and competitive landscapes for each sector.
Three GLP-1 weight-loss drugs—semaglutide, tirzepatide and retatrutide—reduced weight and improved metabolic health in mice lacking the MC4R gene, offering potential treatment for rare genetic obesity.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07611097 |
Osteoporosis and Sarcopenia Prevention in Middle-Aged Population |
NOT_YET_RECRUITING | NA |
| NCT07609329 |
Preoperative Immunonutrition in Patients With Bone and Soft Tissue Sarcomas |
RECRUITING | NA |
| NCT07609160 |
Effectiveness of Combined GLP-1 Receptor Agonist Therapy and Structured Exercise on Skeletal Muscle Morphology, Quality, and Physical Function in Overweight and Obese Individuals |
NOT_YET_RECRUITING | NA |
| NCT07607236 |
Muscle Ultrasound for Sarcopenia Assessment in Kidney Transplant Recipients |
NOT_YET_RECRUITING | |
| NCT07601321 |
BCW-Based Resistance Training for Community-Dwelling Sarcopenia Patients |
NOT_YET_RECRUITING | NA |
| NCT07600866 |
Validation of a Body-Composition Segmentation Software on a Diverse Public CT Scan Cohort |
NOT_YET_RECRUITING | |
| NCT07597850 |
TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status |
RECRUITING | PHASE2 |
| NCT07586956 |
Serum Insulin-like Growth Factor-1 to Albumin Ratio as a Biomarker for Sarcopenia Severity in End-Stage Renal Disease Patients on Hemodialysis |
NOT_YET_RECRUITING | |
| NCT07580144 |
Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients |
RECRUITING | |
| NCT07575958 |
Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial |
RECRUITING | NA |
