2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension
NCT06025383 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 19
Last updated 2025-05-15
Summary
The objective of this project is to elucidate the effect of L-Citrulline (L-CIT) supplementation on vascular function at rest and during rhythmic handgrip exercise and functional sympatholysis via lower-body negative pressure in postmenopausal women with elevated blood pressure and hypertension.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
L-Citrulline
2 weeks of L-Citrulline supplementation (6 grams/day)
- DIETARY_SUPPLEMENT
-
Placebo
2 weeks of microcrystalline cellulose supplementation (8 capsules/day)
Sponsors & Collaborators
-
Texas Tech University
lead OTHER
Principal Investigators
-
Arturo Figueroa · Texas Tech University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 50 Years
- Max Age
- 70 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-07-20
- Primary Completion
- 2024-07-01
- Completion
- 2024-07-01
Countries
- United States
Study Locations
More Related Trials
-
Effect of Citrulline Malate Supplementation on Physical Function and Biochemical Parameters in Physically Active Older Women
NCT07143305 ·Status: COMPLETED ·Phase: NA
-
Nutraceutical Supplement in the Management of Hypertension
NCT02663479 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Coenzyme Q-10 and Pulmonary Arterial Hypertension
NCT01148836 ·Status: COMPLETED ·Phase: NA
-
Assessment of a Pre-Workout Dietary Supplement
NCT02952014 ·Status: COMPLETED ·Phase: NA
-
The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"
NCT01073332 ·Status: COMPLETED ·Phase: NA
-
The Objective of This Study Was to Compare and Quantify the Bioavailability of Citrulline Byproducts in Blood Samples and in Urine Samples After a Single Dose of the Assigned Dietary Supplement. The Treatment Arms Containing the Following Molecules: Citrulline HCL and L-Citrulline,
NCT06977854 ·Status: COMPLETED
-
Prospective Safety and Tolerability Assessment of a Cardiovascular Health Dietary Supplement
NCT02452749 ·Status: COMPLETED ·Phase: NA
-
Cardiac and Vascular Responses to Creatine Supplementation in Elderly Men
NCT05329480 ·Status: RECRUITING ·Phase: NA
-
Influence of Microfiltered-seawater Supplementation and Variable Resistance Training in Blood Pressure, Oxidative Stress, Hepatic, and Renal Biomarkers in Older Women
NCT06600243 ·Status: COMPLETED ·Phase: NA
-
Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration
NCT03998800 ·Status: COMPLETED ·Phase: NA
-
Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation
NCT05313490 ·Status: UNKNOWN ·Phase: NA
-
Assessment of a Pre-Workout Supplement
NCT03022604 ·Status: COMPLETED ·Phase: NA
-
Safety & Efficacy of Nicotinamide Riboside Supplementation for Improving Physiological Function in Middle-Aged and Older Adults
NCT02921659 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effects of L-Arginine and Citrulline Malate Supplementation on Sport Performance in Physically Active Men
NCT06938126 ·Status: COMPLETED ·Phase: NA
-
Urolithin A Supplementation in Middle-aged Adults With Obesity
NCT05921266 ·Status: COMPLETED ·Phase: NA
-
Bioavailability and Impact of Coenzyme Q10 in Stressing Exercise in Senescence Athletes
NCT03893864 ·Status: COMPLETED ·Phase: PHASE1
-
Flaxseed Lignan Supplementation in Elderly Participants With Stage I Hypertension
NCT02391779 ·Status: COMPLETED ·Phase: PHASE2
-
Strength Training and Resveratrol
NCT06585865 ·Status: RECRUITING ·Phase: NA
-
Long-Term Effect of Combined Citrulline and Nitrate-Rich Beetroot Extract Supplementation
NCT05143879 ·Status: COMPLETED ·Phase: NA
-
Creatine Monohydrate Supplementation and Vascular Endothelial Health
NCT05014659 ·Status: COMPLETED ·Phase: NA
-
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
NCT06613542 ·Status: COMPLETED ·Phase: NA
-
Effects of TA-65, a Telomerase Activator on Metabolic Syndrome
NCT02531334 ·Status: COMPLETED ·Phase: NA
-
Nitrate and Exercise Performance in Middle to Older Aged Adults
NCT03371966 ·Status: COMPLETED ·Phase: NA
-
TetraSOD® Supplementation and Exercise Performance
NCT06831656 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Sports Supplements on Blood Flow
NCT04278053 ·Status: COMPLETED ·Phase: NA