MedTrace Logo

Effects of L-arginine and L-citrulline Supplementation on Muscle Respiration

NCT03998800 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 18

Last updated 2022-05-02

No results posted yet for this study

Summary

The objective of this trial is to determine the effects of dietary supplementation with the amino acids, L-arginine and L-citrulline, on endurance performance and mitochondrial respiration in healthy men compared to supplementation with L-arginine alone and a placebo supplement.

Conditions

  • Dietary Exposure

Interventions

DIETARY_SUPPLEMENT

Dietary Supplement

Dietary Supplement: L-arginine and L-citrulline supplement, L-arginine supplement, or placebo supplement (corn-starch) Subjects will complete 3 individual 10 day supplementation periods, separated by washout periods of approximately 2 weeks.

BEHAVIORAL

Endurance exercise on a cycle ergometer

On day 10 of each supplementation period, subjects will complete a performance test on a cycle ergometer to investigate their endurance performance.

Sponsors & Collaborators

  • Kyowa Hakko Bio Co., Ltd.

    collaborator INDUSTRY

  • Loughborough University

    lead OTHER

Principal Investigators

  • Stephen J Bailey, PhD · Lecturer

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-05-01
Primary Completion
2022-01-01
Completion
2022-01-01

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03998800 on ClinicalTrials.gov