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The Effect of Short-term L-citrulline Supplementation on Blood Pressure and Arterial Stiffness

NCT05974813 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2023-08-03

No results posted yet for this study

Summary

The goal of this clinical trial is to examine the effect of short-term L-Citrulline on central and peripheral blood pressure in healthy older adults. The main questions it aims to answer are:

* Does L-citrulline favorably affect blood pressure at rest and during exercise?
* Does L-citrulline favorably affect arterial stiffness?
* Does L-citrulline favorably affect muscle oxygenation at rest and during exercise?

Participants will be asked to consume L-citrulline and a placebo for six days and participate in the evaluation of their blood pressure, arterial stiffness, and muscle oxygenation before and after each intervention.

Researchers will compare L-citrulline and placebo groups to examine whether L-citrulline supplementation affects the above health parameters.

Conditions

  • Blood Pressure

Interventions

DIETARY_SUPPLEMENT

L-Citrulline

6 g (3 g every 12 h) of L-citrulline for six days

DIETARY_SUPPLEMENT

Placebo

6 g (3 g every 12 h) of maltodextrin for six days

Sponsors & Collaborators

  • European University Cyprus

    lead OTHER

Principal Investigators

  • Marios Vryonides, Dr. · European University Cyprus

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
55 Years
Max Age
70 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-03-01
Completion
2023-03-01

Countries

  • Cyprus

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05974813 on ClinicalTrials.gov