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The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization

NCT05814705 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2024-10-02

No results posted yet for this study

Summary

There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain foods can help reduce these declines. Recent research suggests that Urolithin A, which is a natural compound that can be produced after eating pomegranates, nuts, and berries, improves muscle health. In this study, the investigators aim to investigate if a protein beverage (standard care during disuse) with or without Urolithin A can reduce or prevent the loss of muscle health while wearing a knee brace (muscle disuse).

Conditions

  • Healthy
  • Muscle Disuse Atrophy

Interventions

DIETARY_SUPPLEMENT

Protein supplement

Ready-to-drink protein beverage consumed once daily for 28 days

DIETARY_SUPPLEMENT

Protein supplement with Urolithin A

Ready-to-drink protein beverage with 1000 mg of Urolithin A consumed once daily for 28 days

Sponsors & Collaborators

Principal Investigators

  • Stuart Phillips · McMaster University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-01
Primary Completion
2024-05-31
Completion
2025-04-30

Countries

  • Canada

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05814705 on ClinicalTrials.gov