A first-in-human T-cell therapy showed lasting benefit in children with DIPG and relapsed CNS tumors, while a preclinical mRNA vaccine reduced neuroblastoma tumor size by 70%. Aneuploidy predicted response to olaparib plus irinotecan.
A Senate subcommittee heard testimony that mRNA COVID vaccines were considered the likely cause in 73.9% of post-vaccine deaths in a large autopsy series. Separately, NEJM research identified the K31E antibody mutation and adenovirus protein pVII as triggers of rare VITT blood clots. The findings may enable safer adenoviral vaccines.
Studies reveal context-dependent genetic effects in psychiatric disorders, reassuring evidence on prenatal antidepressant use, and findings on parental depression timing, diagnostic interview reliability, and rising self-diagnosis.
Researchers at McMaster University said their SyntheMol-RL AI model designed a new antibiotic candidate called synthecin. In mouse wound infection models, the topical compound was highly effective against drug-resistant Staphylococcus aureus.
International researchers have identified a specific antibody mutation that causes rare but serious blood clots after adenovirus-based COVID-19 vaccines or natural adenovirus infection, providing a roadmap for safer vaccine design.
New research shows wearable devices can predict depression relapses weeks in advance through sleep pattern analysis, while studies reveal limitations in Apple Watch blood pressure alerts and benefits of replacing TV time with physical activity.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07781995 |
AI-Adaptive AR Training for Balance and Falls Prevention in Older Adults |
NOT_YET_RECRUITING | NA |
| NCT07760675 |
Evaluating in Person Curriculum for Educating Obstetrical Residents on Better Caring for 2 Spirit Metis Patients Using and AI Assisted OSCE. |
NOT_YET_RECRUITING | NA |
| NCT07759635 |
The Influence of Plan B® on Cardiovascular Health. |
RECRUITING | NA |
| NCT07758036 |
Group CBT for Paternal Perinatal Depression |
NOT_YET_RECRUITING | NA |
| NCT07739719 |
SAFE (Self-Administration of Flumist to ImprovE Uptake: A Household-Based Cluster Randomized Trial) |
NOT_YET_RECRUITING | PHASE4 |
| NCT07697287 |
Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment |
ACTIVE_NOT_RECRUITING | PHASE4 |
| NCT07697261 |
Fatigue in Long COVID |
NOT_YET_RECRUITING | NA |
| NCT07693803 |
The Creative Team Member: A Study of the Influence of AI Integration Timing on Brainstorming and Ideation |
NOT_YET_RECRUITING | NA |
| NCT07678632 |
Prevention of Vascular Graft Infection With Hypochlorous Acid |
NOT_YET_RECRUITING | NA |
| NCT07673770 |
Brain Wave Informed Non-invasive Brain Stimulation: Improving Neural Networks of Working Memory in Dementia: a Proof-of-concept Study |
RECRUITING | NA |
