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Supraspinal Processing of Sensory Aspects of Pain

NCT05814497 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 350

Last updated 2025-07-01

No results posted yet for this study

Summary

The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients. The main questions it aims to answer are:

* Are there shared and distinct brain systems engaged by different forms of pediatric chronic pain?
* What are predictors of recovery from chronic pain?
* What brain systems are associated with the spread of pain?

For this study participants will undergo:

* Functional Magnetic Resonance Imaging (fMRI)
* Quantitative Sensory Testing
* Psychological Assessments

Conditions

  • Migraine in Children
  • Complex Regional Pain Syndromes
  • Musculoskeletal Pain
  • Functional Abdominal Pain Syndrome
  • Fibromyalgia

Interventions

OTHER

Multisensory Task

Reversing checkerboard, tones, and finger opposition.

OTHER

Graphesthesia

Trace numbers on skin.

OTHER

Divided attention

Divide attention between two noxious stimuli.

Sponsors & Collaborators

  • University of Barcelona

    collaborator OTHER

  • Children's Hospital Medical Center, Cincinnati

    lead OTHER

Principal Investigators

  • Robert Coghill, PhD · Children's Hospital Medical Center, Cincinnati

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SINGLE_GROUP

Eligibility

Min Age
10 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2027-06-30
Completion
2027-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05814497 on ClinicalTrials.gov