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Shifting Away From Pain: Neurocognitive Approach to Explain and Predict Recovery Following Whiplash Injury

NCT05161767 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 37

Last updated 2024-01-12

No results posted yet for this study

Summary

Around half of the patients with neck pain after trauma (whiplash) will develop chronic pain. Understanding the transition from acute to chronic pain after whiplash is a priority since will help to identify those which patients are likely to fully recover and who do not. In the last years, there have been a call for an investigation of new biomarkers; particularly in brain structure and function. Alterations in the structure of the brain (gray matter, white matter and cortical thickness) as well as the brain function have been found in people with chronic WAD; which are also correlated with pain, disability and symptoms of central sensitization such as hyperalgesia. Previous research has found structural and functional brain differences between people who develop chronic low back pain compared to those who recovered; but research in this vein is still lacking in people with whiplash. Consequently, this study aims to examine the neural correlates of recovery following whiplash injury.

Conditions

  • Whiplash Injuries

Interventions

DIAGNOSTIC_TEST

Brain MRI (neuroimaging)

Structural and functional brain scans will be taken.

Sponsors & Collaborators

  • University Ghent

    lead OTHER

Principal Investigators

  • Iris Coppieters, PhD · Vrije Universiteit Brussel, KU Leuven

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-06
Primary Completion
2024-01-10
Completion
2024-01-10

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05161767 on ClinicalTrials.gov