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Genes Variability in Obesity and Normal Body Weight Patients.

NCT05789888 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 116

Last updated 2023-03-29

No results posted yet for this study

Summary

The goal of this clinical trial is to learn about variability of gene SCD and MT-ATP6 in describe participant population and health conditions. The main questions it aims to answer are:

• whether there is variation in genes between obese and normal weight individuals

Participants will get body weight and high was assessed using the medical scale and stadiometer, then, basis on obtained results, the Body Mass Index (BMI) will be calculated. Next, participants get determine the body composition and body composition analysis by bioelectrical impedance method to determined: Visceral Adipose Tissue (VAT in cm2 and %), Subcutaneous Adipose Tissue (SAT in cm2 and %), and the VAT/SAT ratio was also determined. Then order to examine the sequence of the genes, swab will take from the oral cavity (cheeks and palate) using sterile swab. The research was carried out at the Department of Dietetics and Clinical Nutrition (Medical University of Bialystok).

Conditions

Interventions

GENETIC

MT-ATP6 mtDNA gene variability in obesity and normal body weight patients.

As part of the research, the MT-ATP6 gene was tested in order to influence the modulation of the amount of fat contained.

GENETIC

SCD gene variability in obesity and normal body weight patients.

As part of the research, the SCD gene was tested in order to influence the modulation of the amount of fat contained.

OTHER

Finding TOFI and FOTI phenotypes in participants with obesity and normal weight.

As part of the research, we measured the amount of VAT and SAT and calculate VAT/SAT ratio as a marker to determine the phenotype of fat tissue.

Sponsors & Collaborators

  • Medical University of Bialystok

    lead OTHER

Principal Investigators

  • Damian D Pogodziński, Master · Medical University of Białystok

Eligibility

Min Age
20 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-04-10
Primary Completion
2023-01-01
Completion
2023-01-01

Countries

  • Poland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05789888 on ClinicalTrials.gov