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Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease

NCT00510588 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2014-12-03

No results posted yet for this study

Summary

Chronic inflammatory activation in fat tissue can be the link between adiposity and an increased risk for atherosclerosis. Aim of the study is to investigate how molecular alterations in fat tissue can be influenced by regular physical exercise training alone or in combination with a medical therapy (Glitazon or Metformin) in obese patients with stable CAD and impaired glucose tolerance.

Conditions

  • Stable Coronary Artery Disease
  • Obesity
  • Impaired Glucose Tolerance

Interventions

OTHER

training

regular physical exercise training for 6 months

OTHER

training + metformin

regular physical exercise training in combination with metformin for 6 months

OTHER

training + glitazon

regular physical exercise training in combination with a glitazon for 6 months

Sponsors & Collaborators

  • University of Leipzig

    lead OTHER

Principal Investigators

  • Gerhard Schuler, Prof. of medicine · Heart Center Leipzig - University Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2013-10-31
Completion
2013-10-31

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00510588 on ClinicalTrials.gov