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Evaluation of Lipoedema Tissue Transcriptome

NCT05861583 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2023-07-27

No results posted yet for this study

Summary

Lipoedema is a chronic painful disease with a fat distribution disorder affecting women. It is probably aggravated by hormonal changes. It is also discussed that a genetical predisposition might be a risk factor for developing lipoedema. The mechanisms leading to lipoedema are mostly unknown. The aim of this study is to identify molecular mechanisms and changes of the RNA-Expression pattern causing lipoedema by comparing the transcriptome of subcutaneous tissue of lipoedema patients vs. healthy subcutaneous tissue.

Conditions

  • Lipedema

Interventions

OTHER

fat tissue

fat tissue sample collected while cosmetical liposuction

OTHER

lipoedema tissue (stage 1)

lipoedema tissue sample (stage 1) collected while medical liposuction

OTHER

lipoedema tissue (stage 2)

lipoedema tissue sample (stage 2) collected while medical liposuction

OTHER

lipoedema tissue (stage 3)

lipoedema tissue sample (stage 3) collected while medical liposuction

Sponsors & Collaborators

  • Hanse-Klinik, Fachklinik für Liposuktion, Lübeck

    collaborator UNKNOWN

  • Praxisklinik Kronshagen, Kiel-Kronshagen

    collaborator UNKNOWN

  • University Hospital Schleswig-Holstein

    lead OTHER

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2023-12-01
Completion
2024-03-01

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05861583 on ClinicalTrials.gov