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Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project

NCT05649800 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2025-12-01

No results posted yet for this study

Summary

The goal of this observational study is to determine the feasibility of using integrated Transcranial Doppler Ultrasonography or Near Infrared Spectroscopy to detect changes in cerebral autoregulation and neurovascular coupling in healthy, stroke, dementia, depression and delirium populations. We also aim to:

* Determine the optimal stimulus for neurovascular coupling
* To derive sample size estimates for a future study
* To develop a multilevel, multivariate model that can be applied to future datasets

Conditions

Sponsors & Collaborators

  • University of Leicester

    lead OTHER

Principal Investigators

  • Dr Jatinder Minhas · Clinical Associate Professor of Stroke Medicine

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-03-17
Primary Completion
2025-11-26
Completion
2026-08-26

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05649800 on ClinicalTrials.gov