Also known as: non-fatal stroke, nonfatal stroke
Stroke occurs when blood flow to part of the brain is blocked or when a cerebral blood vessel ruptures, causing brain injury due to ischemia or hemorrhage. It is a major cause of death and long-term disability.
Sentante secured CE-mark approval for its multi-domain robotic platform and was accepted into the FDA’s total product life cycle advisory programme. The moves support European commercialization and planning for remote stroke thrombectomy clinical studies.
Research in the United Kingdom found that preventing type 2 diabetes cut care-related greenhouse gas emissions by about 67%, while well-controlled disease was linked to 21% lower emissions than uncontrolled diabetes.
Vermont insurers and employers are scaling back GLP-1 coverage as costs rise, leaving some patients without access. The drugs remain in high demand as studies point to benefits beyond weight loss.
A study in the American Journal of Medicine found that U.S. adults with the highest ultraprocessed food intake had higher cardiovascular disease risk. Mean ultraprocessed food intake was 26.1% of total energy.
Two retrospective studies in type 2 diabetes patients with unruptured intracranial aneurysms linked GLP-1RAs to lower non-traumatic subarachnoid haemorrhage risk. One study also showed lower all-cause mortality over five years.
Phase 3 OCEANIC-STROKE data showed asundexian plus antiplatelet therapy reduced recurrent ischemic stroke versus placebo. Major bleeding rates were similar between groups.
GLP-1 drugs are still being studied for Alzheimer’s and addiction after semaglutide failed to slow cognitive decline in Alzheimer’s. A 2025 abstract reported semaglutide slowed cognitive impairment in an Alzheimer’s model.
The FDA approved Endospan’s NEXUS Aortic Arch Stent Graft, enabling US commercial launch. Approval was supported by one-year TRIOMPHE study results in high-risk surgical patients.
Recent studies reveal AI chatbots face significant challenges in medical applications, with one study showing ChatGPT Health under-triaged 51.6% of emergency cases. Cancer patients using an AI chatbot experienced 22% withdrawal rates due to usability issues, while medical researchers show cautious adoption with 40.3% reporting AI use in research.
Transformative therapies including stem cell transplant and gene therapy offer sickle cell disease patients potential freedom from the SCD phenotype with reduced morbidities. About 90% of patients successfully switch to donor blood cell production after transplant, while gene therapies work by editing the patient's own stem cells. These treatments require careful consideration of disease severity and potential risks including major adverse events.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07605039 |
Structural Mechanisms of Dual-Target tDCS in Stroke Hemiparetic Hand |
NOT_YET_RECRUITING | NA |
| NCT07604181 |
Comparative Effects of Telerehabilitation and Clinic Based Constraint Induced Movement Therapy on Upper Limb Function in Sub-Acute Stroke Patients |
RECRUITING | NA |
| NCT07603440 |
Intravenous Thrombolysis With Tenecteplase Plus Thrombectomy Versus Thrombectomy Alone In Patients With A Large Ischemic Stroke: A Multicenter Randomized Controlled Trial (IVT-ALL-IN) |
NOT_YET_RECRUITING | PHASE3 |
| NCT07603102 |
Mindfulness With Dual-Task Training in Post-Stroke Mild Cognitive Impairment |
RECRUITING | NA |
| NCT07601659 |
Prospective Italian Validation of SMS in Patients With Suspected Acute Stroke |
NOT_YET_RECRUITING | |
| NCT07601633 |
Split-Belt Gait Retraining in Subacute Stroke |
NOT_YET_RECRUITING | NA |
| NCT07598695 |
Sensory Feedback and Hand Motor Adaptation |
RECRUITING | EARLY_PHASE1 |
| NCT07598435 |
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke |
RECRUITING | NA |
| NCT07597226 |
Virtually Assisted Home Rehabilitation After Stroke for Underserved Texas Communities |
NOT_YET_RECRUITING | NA |
| NCT07594938 |
Studying Fatigue and Movement After Stroke |
NOT_YET_RECRUITING |
