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Imaging and Serological Biomarkers of Autonomic Dysfunction After Ischemic Stroke

NCT06740942 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-05-07

No results posted yet for this study

Summary

The goal of this observational study is to

* to investigate the prevalence and time course of autonomic dysfunction in acute ischemic stroke patients;
* to evaluate the influence of lesion location on autonomic dysfunction;
* to identify patterns of structural and functional brain connectivity within the central autonomic control circuits associated with autonomic dysfunction; and
* to explore causal models of the link between brain lesions; cardiac, immunological and endocrine biomarkers; and dysautonomia.

Researchers will compare patients with acute ischemic stroke to patients with transient ischemic attacks to study the effect of acute ischemic brain lesions.

Participants will

* undergo cardiovascular autonomic function testing;
* receive structural and functional MR imaging;
* provide blood samples for determinaton of serological biomarkers auf dysautonomia.

Conditions

  • Acute Ischemic Stroke
  • Transient Ischemic Attack

Sponsors & Collaborators

  • Universitätsklinikum Hamburg-Eppendorf

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-04
Primary Completion
2026-09-30
Completion
2026-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06740942 on ClinicalTrials.gov