APPETITE: Plant Protein and Exercise Solutions for the Prevention of Undernutrition in Older Adults.

Summary

The APPETITE Trial aims to investigate the efficacy of innovative plant protein fibre (PPF) products (developed in a previous workpackage) as part of a personalised diet with/out physical activity on appetite and incidence of undernutrition in older persons from three European countries at high risk of undernutrition.

Conditions

• Appetite Loss
• Physical Inactivity
• Undernutrition
• Anorexia of Aging
• Aging
• Ageing Well

Interventions

BEHAVIORAL

Physical activity intervention

The 12 week intervention will involve 2 weekly group exercise sessions incorporating strength and balance exercises, along with home-based exercise focused on increasing time spent walking.

DIETARY_SUPPLEMENT

Personalised nutrition intervention

Two Plant-based Protein and Fibre (PPF) product products have been selected from six initially developed, with best amino acid blend, taste, and bioavailability. Participants will be provided with the PPFs to consume daily as part of a personalised diet over 12 weeks.

Sponsors & Collaborators

• Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

  collaborator OTHER

• Friedrich-Alexander-Universität Erlangen-Nürnberg

  collaborator OTHER

• University of Padova

  collaborator OTHER

• University College Dublin

  lead OTHER

Principal Investigators

• Helen M Roche, Professor · UCD

• Katy Horner, PhD · University College Dublin

• Marjolein Visser, PhD · VU Amsterdam

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

65 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-09-22

Primary Completion

2024-07-17

Completion

2025-09-30

Countries

• Germany
• Ireland
• Italy

Study Locations