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Effects of Non-surgical Periodontal Therapy on Severe Periodontitis and Hyperlipidemia

NCT05548933 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 64

Last updated 2022-09-22

No results posted yet for this study

Summary

This study was a single-center, non-randomized, parallel-group design clinical trial, and each group was assigned a 1:1 ratio with or without hyperlipidemia. Both groups underwent periodontal non-surgical treatment, and blood and gingival crevicular fluid were collected before surgery, 1 month and 3 months after surgery for the detection of MCP-1, IL-8, oxLDL, TNF-α, TG, LDL-C, HDL-C.

Conditions

  • Periodontitis Chronic Generalized Severe
  • Hyperlipidemia
  • Gingival Crevicular Fluid
  • Serum
  • Biomarkers
  • Non-surgical Periodontal Therapy

Interventions

PROCEDURE

non-surgical periodontal therapy

supragingival scaling,subgingival scaling

Sponsors & Collaborators

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-20
Primary Completion
2023-11-01
Completion
2023-11-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05548933 on ClinicalTrials.gov