MedTrace Logo

Nasturtium (Tropaeolum Majus L) Intake and Biochemical Parameters in Pre-diabetic Subjects in Bogota Colombia

NCT05346978 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2022-04-26

No results posted yet for this study

Summary

Brassicaceae plant family have a high content of bioactive compounds such as e.g. glucosinolates (GSLs) and isothiocyanates (ICTs) associated, recently, with diabetes prevention. This research proposal has the intention of evaluating if the ingestion of freeze-dried nasturtium has a positive effect on the insulin response, lipid profile, oxidative stress biomarkers and gene expression of RESISTIN, GLUT 4, acetyl-CoA carboxylase-a (ACC), fatty acid synthase (FASN), NRF-2, NQO1, SFRXN1, glutathione peroxidase 2 (GPx-2), FOXO1, FOXO3 and FOXO6 in subjects with glucose intolerance.

Conditions

  • Pre Diabetes

Interventions

DIETARY_SUPPLEMENT

Nasturtium (Tropaeolum majus)

Freeze dried nasturtium (Edible flower)

DIETARY_SUPPLEMENT

Placebo

collagen colored with green pigment used in the food industry

Sponsors & Collaborators

  • Leibniz Institute of Vegetable and Ornamental Crops (IGZ)

    collaborator UNKNOWN

  • University Medical Center Freiburg

    collaborator OTHER

  • Javeriana University

    lead OTHER

Principal Investigators

  • Valentina Guzman, PhD · Pontificia Universidad Javeriana

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-06-01
Primary Completion
2021-11-15
Completion
2021-11-15

Countries

  • Colombia

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05346978 on ClinicalTrials.gov