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Assessment of Neurodevelopmental Needs in Duchenne Muscular Dystrophy

NCT05280730 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2025-08-14

No results posted yet for this study

Summary

Duchenne Muscular Dystrophy is a genetic disease that causes progressive muscle weakness. There is now substantial evidence that boys with this disease do not demonstrate age-related gains in their cognitive skills.

The goals of this study are (i) to use a technology-enabled neurobehavioral assessment called National Institutes of Health Toolbox Cognition Battery (NIHTB-CB) to assess brain development over time; (ii) engage with key-stakeholders to understand how neurodevelopmental problems like attention-deficit hyperactivity, autism spectrum affects individuals (and/or) families, so that we can understand meaningful effects of a potential treatment at an individual level, and (iii) to investigate using brain magnetic resonance imaging (MRI) changes in brain connectivity.

Conditions

Interventions

OTHER

No intervention

There is no intervention

Sponsors & Collaborators

  • Northwestern University

    collaborator OTHER

  • University of Rochester

    collaborator OTHER

  • Virginia Commonwealth University

    lead OTHER

Principal Investigators

  • Mathula Thangarajh, MD, PhD · Virginia Commonwealth University

Eligibility

Min Age
3 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-02-02
Primary Completion
2024-09-30
Completion
2024-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05280730 on ClinicalTrials.gov