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Longitudinal Study of the Natural History of Duchenne Muscular Dystrophy (DMD)

NCT00468832 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 551

Last updated 2016-04-21

No results posted yet for this study

Summary

The purpose of this study is to establish the largest long-term assessment of people with Duchenne muscular dystrophy (DMD). In this study, the investigators associated with the Cooperative International Neuromuscular Research Group CINRG) will take a detailed look (for a minimum of eight years) at DMD participant's physical abilities, the medical problems they experience, and how they use health care services. Physical abilities will be compared to a group of healthy controls.

The second purpose of this study is to find out whether small, normal differences in the genetic makeup of people with DMD (called "single nucleotide polymorphisms" or "SNPs") affect how their disease progresses and relates to muscle strength/size and steroid response.

The third purpose of this study is to study genetic variations associated with DMD.

The final purpose of this study is to determine whether certain biomarkers are present in people with DMD and not in healthy controls.

Conditions

Sponsors & Collaborators

  • U.S. Department of Education

    collaborator FED

  • National Institutes of Health (NIH)

    collaborator NIH

  • United States Department of Defense

    collaborator FED

  • Parent Project Muscular Dystrophy

    collaborator OTHER

  • Cooperative International Neuromuscular Research Group

    lead NETWORK

Principal Investigators

  • Craig McDonald, MD · University of California, Davis

Eligibility

Min Age
2 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • United States
  • Argentina
  • Australia
  • Canada
  • India
  • Israel
  • Italy
  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00468832 on ClinicalTrials.gov