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Study of Focal Airway Disease in Asthma Using Image Guided Bronchoscopy

NCT04514913 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2026-03-06

No results posted yet for this study

Summary

This is a single center study of 60 subjects including those with asthma and mucus plugging, those with asthma and without mucus plugging, and healthy controls. Screening data will be reviewed to determine participant eligibility. Participants who meet all inclusion criteria will participate in image-guided bronchoscopy ("virtual navigation bronchoscopy" \[VNB\]) to sample airway biospecimens in mucus plugged and control airways.

Conditions

  • Asthma
  • Mucus; Plug, Tracheobronchial

Interventions

RADIATION

Multidetector Computed Tomography (MDCT) Scan

This is a low-dose CT scan of the chest using no contract material.

PROCEDURE

Virtual Navigation Bronchoscopy (VNB)

This is a procedure where a camera will be inserted into the lung in order to guide sample collection of bronchoalveolar lavages, bronchail brushes and endobronchial biopsies.

Sponsors & Collaborators

Principal Investigators

  • John Fahy, MD, MSc · University of California, San Francisco

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-28
Primary Completion
2023-02-09
Completion
2023-02-09

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04514913 on ClinicalTrials.gov