Effect of AIRVO Heated Humidification in Bronchiectasis

Summary

The aim of the study is to investigate whether long-term heated humidification therapy (AIRVO) administrated for 1 year over-night on top of standard therapy can reduce the number of exacerbations in adults with non-cystic fibrosis bronchiectasis.

Conditions

• Bronchiectasis Adult

Interventions

DEVICE

Over-night treatment with myAIRVO2

Gas flow will be set between 20 and 30 l/min, according to patient's comfort, and administrated via nasal canula. Temperature will be set at 37°C. If the patient was already in nocturnal oxygen therapy FiO2 will be set according to the prescription.

Sponsors & Collaborators

• ASST Fatebenefratelli Sacco

  collaborator OTHER

• Fondazione IRCCS Policlinico San Matteo di Pavia

  collaborator OTHER

• Ospedale Maggiore Di Trieste

  collaborator OTHER

• Azienda Ospedaliero-Universitaria di Modena

  collaborator OTHER

• Fondazione Policlinico Universitario Agostino Gemelli IRCCS

  collaborator OTHER

• Fondazione Salvatore Maugeri

  collaborator OTHER

• Università degli Studi di Ferrara

  collaborator OTHER

• Azienda Ospedaliero, Universitaria Pisana

  collaborator OTHER

• IRCCS Azienda Ospedaliero-Universitaria di Bologna

  collaborator OTHER

• Ospedale San Paolo

  collaborator OTHER

• Universita degli Studi di Catania

  collaborator OTHER

• Azienda Ospedaliera di Padova

  collaborator OTHER

• University of Palermo

  collaborator OTHER

• Azienda Ospedaliero-Universitaria di Parma

  collaborator OTHER

• University of Foggia

  collaborator OTHER

• Monaldi Hospital

  collaborator OTHER

• Fondazione Don Carlo Gnocchi Onlus

  collaborator OTHER

• Ospedale San Donato

  collaborator OTHER

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

  lead OTHER

Principal Investigators

• Francesco Blasi, Prof · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-06-20

Primary Completion

2025-01-31

Completion

2025-01-31

Countries

• Italy

Study Locations