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Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial

NCT04496232 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2022-08-09

No results posted yet for this study

Summary

Comparing second ejaculate and physiological ICSI (PICSI) as strategies for improvement of abnormal sperm DNA fragmentation in patients undergoing ICSI.

Conditions

  • Male Infertility

Interventions

DEVICE

PICSI

Semen processing by density gradient centrifugation followed by sperm selection by PICSI dishes of the first ejaculate

OTHER

Second ejaculate

Semen processing by density gradient centrifugation for the second ejaculate

Sponsors & Collaborators

  • Ganin Fertility Center

    lead OTHER

Principal Investigators

  • Eman Hasanen · Ganin Fertility Center

  • Radwa Omar · Ganin Fertility Center

  • Hanaa Alkhader · Ganin Fertility Center

  • Hosam Zaki, MSc, FRCOG · Ganin Fertility Center

  • Manar Hozayen, MSc. · Ganin Fertility Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-08-01
Primary Completion
2021-12-01
Completion
2021-12-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04496232 on ClinicalTrials.gov