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Effect of Long-time Human Sperm Storage in Liquid Nitrogen on Semen Parameters

NCT06448000 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 101

Last updated 2024-06-07

No results posted yet for this study

Summary

Sperm cryopreservation is an essential tool for men fertility preservation in the context of gonadotoxic treatments or/and pathologies such as cancers, gamete donation and ART. Nevertheless, it is validated that the freezing and thawing procedures affect sperm parameters and in particular motility. It is therefore essential to determine the impact of storage time on motility and particularly the number of progressive motile spermatozoa which will determine the choice of ART technique. However, few studies have analyzed the impact of storage time in liquid nitrogen and no study over a long period on human spermatozoa and their use in ART.

The aim of this study is to assess the impact of long-time storage, from 2 to 12 years, in liquid nitrogen on standard semen parameters, notably motility.

Conditions

  • Healthy
  • Cancer
  • Infertility, Male
  • Cryopreservation

Sponsors & Collaborators

  • University Hospital, Clermont-Ferrand

    lead OTHER

Principal Investigators

  • Hanae Pons-Rejraji, PhD · University Hospital, Clermont-Ferrand

  • Florence Brugnon, MD, PhD · University Hospital, Clermont-Ferrand

Eligibility

Min Age
19 Years
Max Age
63 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2020-10-31
Completion
2023-03-31

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06448000 on ClinicalTrials.gov