Effectiveness of Oral Hyaluronic Acid in Knee Osteoarthritis
NCT04352322 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 47
Last updated 2020-04-20
Summary
This study was a randomized, double-blind, placebo-controlled study evaluating the efficacy of an oral liquid HA supplement (A+HA) in symptoms relief and improvement of quality of life in knee osteoarthritis patients with mild knee pain.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
A+HA(tm)
oral solution of hyaluronic acid mixture in combination with glucosamine and chondroitin
- DIETARY_SUPPLEMENT
-
Placebo
oral solution with no active ingredients
Sponsors & Collaborators
-
TOP Pharm & Medicalware
collaborator UNKNOWN -
China Medical University Hospital
lead OTHER
Principal Investigators
-
Shyu-Jye Wang, MD · China Medical University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-01-31
- Primary Completion
- 2016-07-31
- Completion
- 2016-07-31
Countries
- Taiwan
Study Locations
More Related Trials
-
Comparing Effect of Autologous Platelet-Rich Plasma Versus Hyaluronic Acid Treatment on Knee Osteoarthritis
NCT04972383 ·Status: COMPLETED ·Phase: PHASE3
-
Hyaluronan Versus NaCl 20 Ml Versus Placebo in Knee Osteoarthritis
NCT00144820 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Hyaluronic Acid vs. Hyaluronic Acid on Knee Osteoarthritis
NCT02625727 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study
NCT01188213 ·Status: COMPLETED ·Phase: NA
-
Effects of Aquamin F on Osteoarthritis of the Knee
NCT00452101 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
L-arginine for Knee Osteoarthritis Patients
NCT06054633 ·Status: RECRUITING ·Phase: NA
-
Safety and Efficacy of JointAlive™ on the Knee-joint Function in Adults With Knee Arthritis
NCT04395547 ·Status: COMPLETED ·Phase: NA
-
Efficacy of 3 Weekly Injections of Hyaluronate in Patients With Ankle Osteoarthritis
NCT00918736 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Hyaluronic Acid Injection in Knee Osteoarthritis
NCT06279507 ·Status: RECRUITING ·Phase: PHASE4
-
Intraarticular Glucose Versus Hyaluronic Acid Injection for Knee Osteoarthrosis
NCT03690232 ·Status: UNKNOWN ·Phase: NA
-
The Impact of Hyaluronic Acid Injections on Osteoarthritic Knee Mechanics
NCT00778076 ·Status: UNKNOWN ·Phase: PHASE4
-
The Combination Effect of Platelet-rich Plasma and Hyaluronic Acid for Knee Osteoarthritis
NCT03290365 ·Status: COMPLETED ·Phase: NA
-
Effects of Glucosamine on Joint Fluid in Osteoarthritis Patients
NCT01074476 ·Status: UNKNOWN ·Phase: NA
-
Comparing Efficacy of PRP Combined With Different Hyaluronan for the Treatment of Knee Osteoarthritis
NCT04931719 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain
NCT00418782 ·Status: TERMINATED ·Phase: PHASE2
-
Additional Effects of Steroid and Dextrose to Hyaluronic Acid on Knee Osteoarthritis
NCT04165902 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy and Safety of Tongren-Dahuoluo Bolus in Patients with Knee Osteoarthritis
NCT06674759 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Traditional Chinese Medicine Formula in the Treatment of Osteoarthritis of Knees or Hips.
NCT04110847 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Cross-linked Hyaluronic Acid in Knee Osteoarthritis
NCT07241442 ·Status: COMPLETED
-
The Role of Synovitis in Osteoarthritis
NCT03167333 ·Status: UNKNOWN ·Phase: NA
-
A Multicentre Clinical Investigation to Assess Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Chondroitin Sulfate in Knee Osteoarthritis
NCT04358120 ·Status: COMPLETED ·Phase: NA
-
a Single Intraarticular Injection of PRP for Early Knee OA
NCT04027738 ·Status: COMPLETED ·Phase: NA
-
Comparative Effectiveness of Hyaluronic Acid Injections for Management of Knee Osteoarthritis
NCT02671565 ·Status: COMPLETED
-
To Assess the Efficacy of Collagen Supplement in Osteoarthritis
NCT04470336 ·Status: COMPLETED ·Phase: NA
-
Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation.
NCT06581094 ·Status: COMPLETED ·Phase: NA